Kholis Audah, Ph.D.

Biography:

Dr. Audah was born and raised in Tangerang, Banten Province, Indonesia.

Experience:

• 2019-present, Director of Research and Community Service (Swiss German University)
• 2015-2019, Vice Director for Research (Swiss German University)
• 2015-present, Faculty Member (Department of Biomedical Engineering, Swiss German University)
• 2009-2012, Assistant Professor and Head of Biochemistry Department and Laboratory (College of Medicine, University of Hail, Saudi Arabia)
• 2014-2015, Faculty Member (Multidisciplinary Graduate Studies, University of Indonesia) Jun-Nov
• 2014, Head of Department of Bioinformatics, Head of Laboratory and Acting Vice Rector for Academic Affairs (the Indonesian International Institute for Life Sciences)
• 2013-2014, Director of Center for Infectious Diseases Research (Surya University)
• 2008-2009, Postdoctoral Research Associate (Yale University School of Medicine)
• 2003-2007, Graduate Teaching Assistant (Auburn University, USA)
• 1998-2001, Graduate Research Assistant (University of Malaya, Malaysia)

Education Background

• Postdoctoral study in Infectious Diseases (Microbial Pathogens) at Yale University School of Medicine, USA (2009).
• Ph.D. in Biochemistry from Auburn University, USA (2007).
• Master’s in Molecular Biology from the University of Malaya, Malaysia (2000)
• Bachelor’s in Chemistry (Biochemistry) from IPB University (1996).

Knowledge Field

• Biomolecules Interactions (Protein-Protein Interactions, DNA-Protein Interactions)
• Drug-Target Interactions, Protein/Enzyme Structure-Function Relationships
• Protein Engineering (Site-Directed Mutagenesis, DNA manipulations)
• Protein Works (expression, isolation and purification, characterization)
• Enzyme Kinetics
• Molecular Biology/Molecular Microbiology
• Medicinal Chemistry
  • Bioinformatics
• Multi-Omics
• Laboratory Design and Instrumentations

Research Interest:

• His research focuses on Drug Discovery from Indonesian Biodiversity and Understanding the Molecular Basis of Microbial Defense Mechanisms (microbial resistant). He developed the Indonesian Natural Products Library (INPL) and Citizen Medicine (CitMed) as the two platforms for Indonesian Biodiversity-based natural medicines databases.
• He is also interested in research fields such Gene/DNA Therapy/Genome Editing and Biomarker Discovery for Diagnostics Purpose and Telemedicine.

Teaching Area:

• Biochemistry
• Protein Engineering
• Enzyme Kinetics
• Molecular Biology
• Microbiology
• Medical Biotechnology
• Bioinformatics
• Omics
• General Biology
• General Chemistry
• Biomaterials
• Clinical Engineering

Publications:

• Elnora Listianto Lie, Tedi Dwi Fauzi Hermawan, Kholis Abdurachim Audah* (2023). Whole genome sequences analyses of Indonesian isolates SARS-CoV-2 variants and their clinical manifestations. The Indonesian Journal of Biotechnology. Vol 28, No 1, pp.1-13. https://doi.org/10.22146/ijbiotech.73783
• Kholis Abdurachim Audah*, Jufendi Ettin, Jason Darmadi, Norma Nur Azizah, Amalda Siti Anisa, Tedi Dwi Fauzi Hermawan, Conny Riana Tjampakasari, Rudi Heryanto, Intan Safinar Ismail and Irmanida Batubara . Indonesian Mangrove Sonneratia caseolaris Leaves Ethanol Extract is Potential Super Antioxidant and Anti Methicillin-Resistant Staphylococcus aureus Drug. Molecules 2022, 27(23), 8369; https://doi.org/10.3390/molecules27238369.
• Kholis Abdurachim and Holly R. Ellis (2006). Detection of Protein-Protein Interactions in the Alkanesulfonate Monooxygenase from E. coli. The Journal of Bacteriology, Vol.188 (23): 8153- 8159.
• Jason Darmadi, Razethy Rahayu Batubara, Sandiego Himawan, Norma Nur Azizah, Hilyatushalihah Kholis Audah, Ade Arsianti, Evi Kurniawaty, Intan Safinar Ismail, Irmanida Batubara, Kholis Abdurachim Audah* (2021). Evaluation of Indonesian Mangrove Xylocarpus granatum Leaves Ethyl Acetate Extract as Potential Anticancer Drug. Nature Scientific Reports Volume 11, Article number 6080 page 1-18.
• Maren Schniederberend, Kholis Abdurachim, Thomas S. Murray, and Barbara Kazmierczak (2013). The GTPase Activity of FlhF Is Dispensable for Flagellar Localization, but Not Motility, in Pseudomonas aeruginosa. The Journal of Bacteriology, Vol.195(5):1051-60.
• Kholis Abdurachim Audah*, Razethy Batubara, Julkipli, Elza Wijaya, Evi Kurniawaty, Irmanida Batubara (2020). Antibacterial Screening of Mangrove Extract Library Showed Potential Activity against Escherichia coli and Staphylococcus aureus. Journal of Tropical Life Sciences. Vol. 10 (2): 105-111.
• Yustinus Maladan, Hana Krismawati, Tri Wahyuni, Ratna Tanjung, Kamla Awaludin, Kholis Abdurachim Audah and Arli Aditya Parikesit. The whole-genome sequencing in predicting Mycobacterium tuberculosis drug susceptibility and resistance in Papua, Indonesia. BMC Genomics 22:844 page 1-11. https://doi.org/10.1186/s12864-021- 08139-3.

Professional Certifications:

• Certified Good Clinical Practice, The Indonesian Association for The Study of Medicinals (2020) (No expiration date)
• Certified Reviewer, Ministry of Research, Technology and Higher Education, Republic of Indonesia and ISO 17024 (2017) (No expiration date)
• Biosafety Level 2 and Radioisotope handling, Yale University (2008) (No expiration date)

Organization:

• 2023-present, Advisory Board Chairman (Masyarakat Bioinformatika dan Biodiversitas Indonesia (MABBI)/ the Indonesian Society for Bioinformatics and Biodiversity)
• 2022-present, Member (the American Society for Tropical Medicine and Hygiene/ ASTMH)
• 2018-2020, Chairman (Masyarakat Bioinformatika dan Biodiversitas Indonesia (MABBI)/ the Indonesian Society for Bioinformatics and Biodiversity)
• 2018-present, Advisory Board Member (Indonesian Society of Biotechnology Study Program
• 2016, Founding President of MABBI 2016-present, Chairman (Yayasan Sabilal Muhtadin, Education for All)
• 2015-present, Executive Member (Indonesian Society for Biochemistry and Molecular Biology)
• 2008-2009, Member (New York Academy of Sciences (By invitation)
• 2008-2009, Member (American Society for Microbiology)